Japan Developing A Lifetime Covid Vaccine Requiring Only One Dose

Japan Developing A Lifetime Covid Vaccine Requiring Only One Dose
Source – The Japan Times

Researchers at the Tokyo Metropolitan Institute of Medical Science are working on a vaccine that might potentially eliminate the need for yearly COVID-19 vaccinations; the vaccine, modelled after the smallpox vaccine, would provide lifelong protection.


Japan Developing A Lifetime Covid Vaccine Requiring Only One Dose

While COVID-19 vaccinations have significantly reduced infections and hospitalisations, it is now clear that their protection does not continue indefinitely and may need frequent supplements as the world enters an endemic phase. Even with the current booster campaign, the government considers adding a fourth dose for increased effectiveness.

Researchers at the Tokyo Metropolitan Institute of Medical Science are working on a vaccine that might potentially eliminate the need for yearly COVID-19 vaccinations; the vaccine, modelled after the smallpox vaccine, would provide lifelong protection.

Source - Fierce Pharma

The smallpox vaccination, created in 1796, is the only vaccine to have eliminated an infectious disease, with the last reported occurrence being in 1977 in Somalia. Michinori Kohara, an emeritus researcher at the Tokyo institute, has been studying the vaccinia virus used in the smallpox vaccination for more than three decades.

Since April 2020, Kohara has been collaborating with the National Institute of Infectious Diseases to create a recombinant vaccinia virus carrying the SARS-CoV-2 virus’s spike protein, which he claims may induce strong neutralising antibodies within a week after injection. Additionally, he said that it retains its efficiency for more than 20 months after a single dose. 

In the first half of 2023, Japanese pharmaceutical company Nobelpharma Co. plans to perform the first and second stages of clinical trials for Kohara’s vaccine in Japan. If these studies are effective, the final phase clinical trial will begin immediately, and the product will be commercialised by 2024.

Source – Lowyat.net

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