First Two Cases Of Delta Plus Variant Detected From Malaysian Students Returning From UK

source – NBC Boston
  • The detection of the country’s first two cases of COVID-19 subvariant Delta AY.4.2 was imported from the United Kingdom by Malaysian students.
  • Both individuals completed the RT-PCR test and were initially reported negative before being confirmed positive following a second test on October 7 during the quarantine period.

First Two Cases Of Delta Plus Variant Detected From Malaysian Students Returning From UK

The Malaysian Ministry of Health (MOH) revealed on November 6 the detection of the country’s first two cases of COVID-19 subvariant Delta AY.4.2, which were imported from the United Kingdom by Malaysian students.

Tan Sri Dr Noor Hisham Abdullah, Director-General of Health, said in a statement today that the cases were discovered when the individuals landed at Kuala Lumpur International Airport (KLIA) on October 2.

Both individuals completed the RT-PCR test and were initially reported negative before being confirmed positive following a second test on October 7 during the quarantine period.

“This sample has undergone full genome sequencing at the Institute of Medical Molecular Biology, Universiti Kebangsaan Malaysia (UMBI-UKM) and the result was released on Oct 30," he said.

According to Dr. Noor Hisham, the AY.4 variety is one of 75 kinds of lineages derived from the Delta variant, and one of the sublineages of AY.4 is the AY.4.2 variant, commonly known as Delta Plus.

“The AY.4.2 variant has two additional mutations to the spike proteins namely Y145H and A222V and as of the end of October 2021, the AY.4.2 variant represents 10 percent of the total full genome sequencing conducted in the UK," he said.

Dr. Noor Hisham said that on October 20, the UK Health Safety Agency recognised AY.4.2 as a variation under investigation (VUI).

The vaccine used now is still effective against this variant and measures such as quarantine, testing, and so on carried out can help reduce the risk of transmission of this variant in Malaysia, especially at the country’s international gateways.”

“MOH will continue to monitor closely to detect the existence of Delta subvariants in the community," he said.

source-the-star

Meanwhile, Dr. Noor Hisham said that ongoing studies at the Institute of Medical Research (IMR) and UMBI-UKM have identified 44 and 46 new cases of the variant of concern (VOC) Delta, respectively (B.1.617.2).

He said that the total number of VOC and VOI (variant of interest) cases is currently 3,782 cases, with 3,762 VOC cases and 20 VOI cases.

To date, there have been 3,522 cases of the Delta variant, 226 cases of Beta, and 14 cases of Alpha, while there have been 13 cases of VOI involving the Theta variant, Kappa (four cases), and Eta (three cases).

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